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Cancer

• A cannabinoid quinone inhibits angiogenesis by targeting vascular endothelial cells
• A pilot clinical study of Δ9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme
• Anandamide Induces Apoptosis in Human Cells via Vanilloid Receptors
• * Antiangiogenic activity of the endocannabinoid anandamide: Correlation to its tumor-suppressor efficacy
• * Anticancer effects of phytocannabinoids used with chemotherapy in leukaemia cells can be improved by altering the sequence of their administration
• Anticancer mechanisms of cannabinoids
• * Antiemetic Effect of Delta-9-Tetrahydrocannabinol in Patients Receiving Cancer Chemotherapy
• Anti-proliferative effects of anandamide in human hepatocellular carcinoma cells
• Anti-tumoral action of cannabinoids on hepatocellular carcinoma: role of AMPK-dependent activation of autophagy
• Antitumor Activity of Plant Cannabinoids with Emphasis on the Effect of Cannabidiol on Human Breast Carcinoma
• Antitumorigenic Effects of Cannabinoids beyond Apoptosis
• * Association between cannabis use and the risk of bladder cancer: results from the California Men’s Health Study
• Cannabidiol (CBD) Priming Enhances Cisplatin Killing Of Cancer Cells
• Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells
• Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells
• Cannabidiol as potential anticancer drug
• Cannabidiol Enhances the Inhibitory Effects of Δ9-Tetrahydrocannabinol on Human Glioblastoma Cell Proliferation and Survival
• Cannabidiol Induces Programmed Cell Death in Breast Cancer Cells by Coordinating the Cross-talk between Apoptosis and Autophagy
• Cannabidiol inhibits angiogenesis by multiple mechanisms
• * Cannabidiol Inhibits Cancer Cell Invasion Via Upregulation Of Tissue Inhibitor Of Matrix Metalloproteinases-1
• Cannabidiol inhibits human glioma cell migration through a cannabinoid receptor-independent mechanism
• Cannabidiol Inhibits Growth and Induces Programmed Cell Death in Kaposi Sarcoma–Associated Herpesvirus Infected Endothelium
• * Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1
• Cannabidiol inhibits paclitaxel-induced neuropathic pain through 5-HT1A receptors without diminishing nervous system function or chemotherapy efficacy
• * Cannabidiolic acid-mediated selective down-regulation of c-fos in highly aggressive breast cancer MDA-MB-231 cells: possible involvement of its down-regulation in the abrogation of aggressiveness
• Cannabinoid-associated cell death mechanisms in tumor models (Review)
• Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma
• Cannabinoid Receptor Agonist as an Alternative Drug in 5-Fluorouracil-resistant Gastric Cancer Cells
• Cannabinoid receptor ligands as potential anticancer agents – high hopes for new therapies
• Cannabinoid Receptor-Mediated Apoptosis Induced by R()-Methanandamide and Win55,212-2 Is Associated with Ceramide Accumulation and p38 Activation in Mantle Cell Lymphoma
• * Cannabinoid receptors as novel targets for the treatment of melanoma
• Cannabinoid Receptors, CB1 and CB2, as Novel Targets for Inhibition of Non-Small Cell Lung Cancer Growth and Metastasis
• * Cannabinoids: A new hope for breast cancer therapy?
• * Cannabinoids and cancer
• * Cannabinoids and cancer: potential for colorectal cancer therapy
• Cannabinoids and cancer: pros and cons of an antitumour strategy
• * Cannabinoids and ceramide: two lipids acting hand-by-hand
• * Cannabinoids and omega-3/6 endocannabinoids as cell death and anticancer modulators
• Cannabinoids as therapeutic agents in cancer: current status and future implications
• Cannabinoids, Endocannabinoids and Cancer
• Cannabinoids for Cancer Treatment: Progress and Promise
• Cannabinoids induce apoptosis of pancreatic tumor cells via endoplasmic reticulum stress-related genes
• Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas
• * Cannabinoids in the treatment of the cachexia-anorexia syndrome in palliative care patients
• Cannabinoids: potential antitumoral agents?
• Cannabinoids Protect Astrocytes from Ceramide-induced Apoptosis through the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway
• Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition
• * Cannabinoids selectively inhibit proliferation and induce death of cultured human glioblastoma multiforme cells
• Cannabis and Cannabinoids (PDQ®) – National Cancer Institute | Patient
• Cannabis and Cannabinoids (PDQ®) – National Cancer Institute | Healthcare Professional
• Cannabis in cancer care
• Cannabis Extract Treatment for Terminal Acute Lymphoblastic Leukemia with a Philadelphia Chromosome Mutation
• CBD inhibits angiogenesis by multiple mechanisms
• * Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer
• Clinical Significance of Cannabinoid Receptors CB1 and CB2 Expression in Human Malignant and Benign Thyroid Lesions
• Comparison of Orally Administered Cannabis Extract and Delta-9-Tetrahydrocannabinol in Treating Patients With Cancer-Related Anorexia-Cachexia Syndrome: A Multicenter, Phase III, Randomized, Double-Blind, Placebo-Controlled Clinical Trial From the Cannabis-In-Cachexia-Study-Group
• COX-2 and PPAR-g Confer Cannabidiol-Induced Apoptosis of Human Lung Cancer Cells
• Delta-9-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo
• * Delta-9-tetrahydrocannabinol interferes with the establishment and the expression of conditioned rejection reactions produced by cyclophosphamide: a rat model of nausea
• Delta-9-tetrahydrocannabinol may palliate altered chemosensory perception in cancer patients: results of a randomized-double-blind, placebo-controlled pilot trial
• * Differential role of cannabinoids in the pathogenesis of skin cancer
• Down-regulation of cyclooxygenase-2 (COX-2) by cannabidiolic acid in human breast cancer cells
• Dronabinol versus megestrol acetate versus combination therapy for cancer-associated anorexia: a North Central Cancer Treatment Group study
• * Endocannabinoids and Cancer
• * Endocannabinoids and fatty acid amides in cancer inflammation and related disorders
• Endocannabinoids as emerging suppressors of angiogenesis and tumor invasion (Review)
• Endocannabinoids as Guardians of Metastasis
• Endocannabinoids in endocrine and related tumours
• Enhancing the Activity of Cannabidiol and Other Cannabinoids In Vitro Through Modifications to Drug Combinations and Treatment Schedules
• Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids Isolated from Cannabis sativa
• Exogenous hepatitis B virus envelope proteins induce endoplasmic reticulum stress: involvement of cannabinoid axis in liver cancer cells
• Expression and Functional Relevance of Cannabinoid Receptor 1 in Hodgkin Lymphoma
• Expression of cannabinoid receptors type 1 and type 2 in non-Hodgkin lymphoma: Growth inhibition by receptor activation
• High level of cannabinoid receptor 1, absence of regulator of G protein signalling 13 and differential expression of Cyclin D1 in mantle cell lymphoma
• Id-1 Is a Key Transcriptional Regulator of Glioblastoma Aggressiveness and a Novel Therapeutic Target
• Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor
• In vitro and in vivo efficacy of non-psychoactive cannabidiol in neuroblastoma
• Increasing Antiproliferative Properties of Endocannabinoids in N1E-115 Neuroblastoma Cells through Inhibition of Their Metabolism
• Inhibition of Cancer Cell Invasion by Cannabinoids via Increased Expression of Tissue Inhibitor of Matrix Metalloproteinases-1
• Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors
• * Inhibition of tumor angiogenesis by cannabinoids
• Integrating cannabis into clinical cancer care
• Involvement of PPARc in the antitumoral action of cannabinoids on hepatocellular carcinoma
• Loss of Cannabinoid Receptor 1 Accelerates Intestinal Tumor Growth
• Marijuana Use and the Risk of Lung and Upper Aerodigestive Tract Cancers: Results of a Population-Based Case-Control Study
• Medical marijuana for cancer
• Medical Marijuana Use in Oncology
• Microarray and Pathway Analysis Reveal Distinct Mechanisms Underlying Cannabinoid-Mediated
• Modulation of breast cancer cell viability by a cannabinoid receptor 2 agonist, JWH-015, is calcium dependent
• Modulation of LPS-Induced Activation of BV-2 Microglial Cells
• Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC: CBD extract and THC extract in patients with intractable cancer-related pain
• Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms
• NTP Toxicology and Carcinogenesis Studies of 1-Trans-Delta(9)-Tetrahydrocannabinol (CAS No. 1972-08-3) in F344 Rats and B6C3F1 Mice (Gavage Studies)
• Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation
• Potentiation of Cannabinoid-Induced Cytotoxicity in Mantle Cell Lymphoma through Modulation of Ceramide Metabolism
• Potentiation of the antitumor activity of adriamycin against osteosarcoma by cannabinoid WIN-55,212-2
• * Preparation and characterisation of biodegradable microparticles filled with THC and their antitumor efficacy on cancer cell lines
• Proapoptotic effect of endocannabinoids in prostate cancer cells
• Receptor-dependent and Receptor-independent Endocannabinoid Signaling: A Therapeutic Target for Regulation of Cancer Growth
• Regulation of nausea and vomiting by cannabinoids
• * Structure-dependent inhibitory effects of synthetic cannabinoids against 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and skin tumour promotion in mice
• Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer
• Targeting CB2-GPR55 Receptor Heteromers Modulates Cancer Cell Signaling
• Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease
• Targeting multiple cannabinoid anti-tumour pathways with a resorcinol derivative leads to inhibition of advanced stages of breast cancer
• The Antitumor Activity of Plant-Derived Non-Psychoactive Cannabinoids
• The cannabinoids: An overview. Therapeutic implications in vomiting and nausea after cancer chemotherapy, in appetite promotion, in multiple sclerosis and in neuroprotection
• * The CB2 cannabinoid receptor signals apoptosis via ceramide-dependent activation of the mitochondrial intrinsic pathway
• The combination of cannabidiol and Δ9-tetrahydrocannabinol enhances the anticancer effects of radiation in an orthotopic murine glioma model
• The effects of cannabidiol and its synergism with bortezomib in multiple myeloma cell lines. A role for transient receptor potential vanilloid type-2
• The endocannabinoid system and cancer: therapeutic implication
• The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation
• The Expression Level of CB1 and CB2 Receptors Determines Their Efficacy at Inducing Apoptosis in Astrocytomas
• The Medical Necessity for Medicinal Cannabis: Prospective, Observational Study Evaluating the Treatment in Cancer Patients on Supportive or Palliative Care
• The potential relevance of the endocannabinoid, 2- arachidonoylglycerol, in diffuse large B-cell lymphoma
• The role of cannabinoids in prostate cancer: Basic science perspective and potential clinical applications
• The role of cannabinoids in the treatment of children with cancer
• The stress-regulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells
• The use of cannabinoids as anticancer agents
• * Therapeutic use of Cannabis sativa on chemotherapy-induced nausea and vomiting among cancer patients: systematic review and meta-analysis
• * Towards the use of cannabinoids as antitumour agents
• United States patent application publication for phytocannabinoids in the treatment of cancer